Pregenetic tesing for aneuploidy and pregenetic Diagnosis

PGS, or preimplantation genetic screening, is a genetic test performed on embryos produced through IVF. PGS gives information about embryos’ genetic health to help your care team select the best embryo for transfer and improve your chance of achieving a successful pregnancy.

How PGS Works
PGS works by looking at the amount of genetic material within IVF embryos. This genetic material is housed within structures called chromosomes.
Embryos with the incorrect number of chromosomes (also called aneuploid embryos) typically do not result in a successful pregnancy or may lead to the birth of a child with a genetic condition. Embryos with the correct number of chromosomes (also called euploid embryos) have a better chance of
leading to a successful pregnancy. PGS identifies embryos with the correct number of chromosomes,and helps to select the embryo with the
best chance of leading to IVF success.

WHO IS PGS FOR?

• Older patients
• Multiple unexplained pregnancy losses
• Multiple failed IVF.
• Genetic Disease in the couple.

All women are at risk of producing chromosomally abnormal embryos. One of the benefits of opting for IVF is that patients may be tested for potential genetic problems before attempting a cycle.

Benefits of PGS

• Higher chance of pregnancy
• Reduced risk of miscarriage
• Elective single embryo transfer
• Reduced number of IVF cycles needed to achieve pregnancy, potentially reducing the time to pregnancy and the costs of extra cycles

The PGS Process

• IVF cycle: Embryos are produced through an IVF cycle.
• Embryo Biopsy: A few cells are carefully removed from the part of the embryo that will form the placenta. Samples are sent to the laboratory while your embryos remain safe at your IVF center.
• PGS: Genetic testing is done at the lab: Transfer & Improved Chance of Success: Embryos most likely to result in success are selected for transfer or can be frozen for future use.